Anti-ESR1 Polyclonal Antibody

商品货号：	商品品牌：	规格	基本售价：	选择规格
K001668P-50ul	solarbio	50ul	960.00元
K001668P-100ul	solarbio	100ul	1600.00元

英文名称	Anti-ESR1 Polyclonal Antibody
别名	ER;ESR;ESRA;ESTRR;Era;NR3A1
应用	WB IHC
稀释比例	WB 1:1000-4000. IHC 1:50-200.
交叉反应	Human Mouse
蛋白分子量	66kDa
Gene ID	2099
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	Recombinant protein of human ESR1
性状	液体
Public Immunogen Range	Recombinant protein of human ESR1
Subcellular Locations	Cell membrane Cytoplasm Cytoplasmic side Cytoplasmic side Golgi apparatus Nucleus Peripheral membrane protein Single-pass type I membrane protein
Swiss Prot	P03372
克隆类型	Polyclonal Antibody
背景资料	This gene encodes an estrogen receptor, a ligand- activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined.